Cannabis Hemp Seed Oil (Cannabis Sativa)
Cannabis Seed Oil or Hemp Seed Oil has a long history of safe and effective use. Hemp Seed Oil is a rich vibrant green and is packed with essential nutrients, including fatty acids, vitamins, terpenes and antioxidants (1-7). Hemp seed oil has many benefits for our skin:
1. Strengthens Skin Barrier
Hemp Seed Oil contains 56% linoleic acid (1), the major essential n-6 fatty acid found naturally in our skin (8). Linoleic acid is the natural precursor for ceramide, a bioactive lipid that plays a role in keeping our skin barrier firm, smooth and healthy (8).
Hemp Seed Oil contains 5% γ-linolenic acid (1). Dietary supplementation with Hemp Seed Oil and other γ-linolenic rich oils such as Evening Primrose Oil, can improve the skin barrier and significantly alleviate symptoms of eczema, including dry skin and itchiness (9-11).
Hemp Seed Oil keeps our skin firm, smooth and healthy.
2. Calms Redness & Irritation
Hemp Seed Oil contains 16% linolenic acid (1), an essential omega 3 fatty acid that calms redness and irritation (8).
Hemp Seed Oil also contains 5% γ-linolenic acid (1), a unique n-6 fatty acid with potent anti-inflammatory activity (12).
Hemp Seed Oil contains β-Caryophyllene (1), a compound with anti-inflammatory activity. β-Caryophyllene is a functional agonist of cannabinoid receptor 2 (CB2). CB2 receptors are expressed on skin cells and immune cells and play an important role in regulating inflammation (13).
- Hemp Seed Oil contains small amounts of β-Myrcene (1), a terpene also found in Mango, Hops and Lemongrass with potent anti-inflammatory activity (13).
β-Caryophyllene is the first compound shown to interact with cannabinoid receptors in the body beyond the cannabis genus (13).
3. Improves Dry Skin
Hemp Seed Oil contains 5% γ-linolenic acid (1).
- Dietary supplementation with Hemp Seed Oil and other γ-linolenic rich oils such as Evening Primrose Oil, can significantly alleviate symptoms of eczema, including dry skin and itchiness (9-11).
- γ-linolenic acid-rich cream has been shown to alleviate dry and itchy skin in patients with chronic kidney disease undergoing dialysis (14).
4. Anti-Acne Potential
Hemp Seed Oil contains 5% γ-linolenic acid (1).
A 10-week, randomised, controlled parallel dietary intervention study was performed in 45 participants with mild to moderate acne, which were given either an omega-3 fatty acid supplement (2,000 mg of EPA and DHA), γ-linolenic acid (400 mg γ-linolenic acid), or control. After 10 weeks of omega-3 fatty acid or γ-linolenic acid supplementation, inflammatory and non-inflammatory acne lesions decreased significantly. Heamatoxylin & eosin staining of acne lesions demonstrated reductions in inflammation and immunohistochemical staining intensity for inflammatory cytokine interleukin-8. This study shows for the first time that omega-3 fatty acid and γ-linolenic acid could be used as adjuvant treatments for acne patients (10).
Hemp Seed Oil contains 11% oleic acid (1), an omega-9 fatty acid found naturally in the protective outer layer of the skin.
- Oleic acid has antimicrobial activity (15) and can increase the antimicrobial peptide beta-defensin-2, which can kill acne-causing bacteria (16).
5. Antioxidant Activity
- Hemp Seed Oil also contains vitamin E, β-sitosterol, phytol and campesterol, compounds with potent antioxidant activity (1).
Note: Cannabis Hemp Seed Oil may contain trace amounts of cannabinoids, including Δ9-tetrahydrocannabinol and cannabidiol
(1).Hemp Seed Oil is rich in key nutrients that play a critical role in maintaining skin barrier, regulating inflammation and protecting against oxidative stress and damage.
Hemp Seed Oil is beneficial for treating dry skin, eczema and acne.
1. Leizer, et al. The Composition of Hemp Seed Oil and Its Potential as an Important Source of Nutrition. J Nutraceut, Funct Med Food. 2000;2(4):35-53.
2. Callaway. Hempseed as a nutritional resource: An overview. Euphytica. 2004;140:65-72.
3. Nissen, et al. Characterization and antimicrobial activity of essential oils of industrial hemp varieties (Cannabis sativa L.). Fitoterapia. 2010 Jul;81(5):413-9.
4. Chen, et al. Analytical characterization of Hempseed (seed of Cannabis sativa L.) oil from eight regions in China. J Diet Suppl. 2010 Jun;7(2):117-29.
5. Chen, et al. The isolation and identification of two compounds with predominant radical scavenging activity in hempseed (seed of Cannabis sativa L.). Food Chem. 2012 Sep 15;134(2):1030-7.
6. Porto, et al. Potential Oil Yield, Fatty Acid Composition, and Oxidation Stability of the Hempseed Oil from Four Cannabis sativa L. Cultivars. J Diet Suppl. 2014 Feb 19.
7. Montserrat, et al. Hemp ( Cannabis sativa L.) Seed Oil: Analytical and Phytochemical Characterization of the Unsaponifiable Fraction. J Agric Food Chem. 2014 Feb 5;62(5):1105-10.
8. McCusker, et al. Healing fats of the skin: the structural and immunologic roles of the omega-6 and omega-3 fatty acids. Clin Dermatol. 2010 Jul-Aug;28(4):440-51.
9. Callaway, et al. Efficacy of dietary hempseed oil in patients with atopic dermatitis. J Dermatolog Treat. 2005 Apr;16(2):87-94.
10. Jung, et al. Effect of Dietary Supplementation with Omega-3 Fatty Acid and gamma-linolenic Acid on Acne Vulgaris: A Randomised, Double-blind, Controlled Trial. Acta Derm Venereol. 2014 Feb 18.
11. Kawamura, et al. Dietary supplementation of gamma-linolenic acid improves skin parameters in subjects with dry skin and mild atopic dermatitis. J Oleo Sci. 2011;60(12):597-607.
12. Kapoor, et al. Gamma linolenic acid: an antiinflammatory omega-6 fatty acid. Curr Pharm Biotechnol. 2006 Dec;7(6):531-4.
13. Russo. Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects. Br J Pharmacol. 2011 Aug;163(7):1344-64.
14. Chen, et al. Therapeutic effect of topical gamma-linolenic acid on refractory uremic pruritus. Am J Kidney Dis. 2006 Jul;48(1):69-76.
15. Chen et al. An innate bactericidal oleic acid effective against skin infection of methicillin-resistant Staphylococcus aureus: a therapy concordant with evolutionary medicine. J Microbiol Biotechnol. 2011 Apr;21(4):391-9.
16. Nakatsuji T, Kao MC, Zhang L, Zouboulis CC, Gallo RL, Huang CM. Sebum free fatty acids enhance the innate immune defense of human sebocytes by upregulating beta-defensin-2 expression. J Invest Dermatol. 2010 Apr;130(4):985-94.
Images from pixabay
Dr. Natasha Ryz, PhD, MSc, BSc, is cofounder of Ryz Rémi Organic Skin Care in Vancouver, Canada. Natasha has a PhD in Experimental Medicine from the University of British Columbia and is a Vanier scholar. She has a strong background in nutrition and holds a Master’s degree and a 4-year Bachelor’s degree in Human Nutritional Sciences.
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